• Offers vitamin B₁₂ in unique blend of adenosylcobalamin and hydroxycobalamin
• Contains Metafolin^® L-5-MTHF, the naturally occurring, universally metabolized form of folate
• Part of the PureGenomics^® product line
• Made with high-quality vegan ingredients backed by verifiable science

Indications

• Ages 18 and up
• Support for common genetic variations^*
• B vitamin and general wellness support^*

Suggested Use

As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.

Science & Research

Verifiable Science

PureGenomics^® B-Complex is designed to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of B vitamins in highly researched and activated forms. Methylation is a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, DNA synthesis, hormone and neurotransmitter production and energy metabolism.¹ Optimal levels of B vitamins have been associated with cellular, cardiovascular, neurological and psychological health.^2,3,4,5 B vitamins are essential to basal mitochondrial function as metabolic coenzymes, playing a key role in energy production and nutrient metabolism.⁶ Folate is offered in this formula as Metafolin^® 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, providing support for individuals with genetic variations in the MTHFR gene.⁷ Vitamin B₁₂ is offered as a combination of hydroxycobalamin and adenosylcobalamin. Hydroxycobalamin is a precursor form of vitamin B₁₂ converted in the body to both methylcobalamin and adenosylcobalamin. Adenosylcobalamin is an activated form stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism and healthy synthesis of neuronal myelin.^{8 Benfotiamine is a lipid-soluble, enhanced-retention thiamin derivative.‡}

References

1. Glier MB, Green TJ, Devlin AM. Mol Nutr Food Res 2014 Jan;58(1):172-82.
2. Antoniades C, et al. Circulation. 2006 Sep 12;114(11):1193-201.
3. den Heijer M, et al. Arterioscler Thromb Vasc Biol. . 1998 Mar;18(3):356-61
4. Jacobs AM, et al. Rev Neurol Dis. 2011;8(1-2):39-47.
5. Almeida OP, et al. Ann Neurol. 2010 Oct;68(4):503-10.
6. Huskisson E, Maggini S, Ruf M. J Int Med Res. 2007 May-Jun;35(3):277-89.
7. Prinz-Langenohl R, et al.Br J Pharmacol. . 2009 Dec; 158(8): 2014?2021.
8. L?vblad K, et al. Pediatr Radiol. 1997 Feb;27(2):155-8.

Warning

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Storage

Store in a cool, dry place.

Source

• Vitamin B¹ (thiamin HCl and benfotiamine), niacinamide, niacin, vitamin B⁵ (calcium pantothenate), vitamin B⁶ (pyridoxal HCl), folic acid (Metafolin^® L-5-MTHF), biotin and choline are synthetic
• Vitamin B² (riboflavin) and vitamin B¹² (hydroxycobalamin and adenosylcobalamin) are derived from corn dextrose fermentation
• Ascorbyl palmitate is produced from corn dextrose fermentation and palm oil