CircuCORE provides the building blocks to support nitric oxide formation which may enhance overall circulation, including heart health and erectile dysfunction. Nitric oxide is a soluble gas that is continually being made from arginine in endothelial cells. Endothelial cells comprise a layer of cells inside the lining of our blood vessels.

Vitamin C (as Ascorbic Acid) –exhibits a wide variety of benefits in the body. In terms of cardiovascular health, vitamin c is valuable for its antioxidant effects. Also, vitamin c aids in the production of collagen and therefore may help to strengthen blood vessel walls.*

Folate (as Quatrefolic® {equivalent to 100 mcg of [6S]-5-Methyltetrahydrofolic acid, glucosamine salt}) – is a member of the B-vitamin family. Adequate dietary intake of folate is needed to stay healthy. Folate performs multiple critical functions related to DNA synthesis and methylation, cell division, growth, development and nervous system function. Folate works together with vitamin B-12 to support normal production of important, mood-regulating neurotransmitters. Furthermore, methylated folate is essential for converting homocysteine to methionine, a process that protects cardiovascular health.

Beet Root Powder – presents some exciting possibilities for supporting cardiovascular health because of its high natural nitrate concentration. Beet root powder may potentially reduce triglycerides, regulate blood pressure and other cardiometabolic processes, and optimize blood flow throughout the body. Supplementing with red beet root powder was shown in a 2016 study to reduce blood pressure, cholesterol, and the inflammatory marker hsCRP. A 2018 study showed that dietary nitrate supplementation in the form of beet juice could help to improve blood flow during exercise in patients with congestive heart failure.

Activin® Grape Seed Extract (vitis vinifera) 100:1 – is a grape seed proanthocyanidin extract. Research studies have shown that ActiVin® possesses a wide range of antioxidant properties. It also demonstrates benefits as an anti-inflammatory agent. These benefits can be helpful in people with cardiovascular disease who may have higher free radical production.

Hawthorn Herb – has traditionally been utilized as a tonic to the heart and circulatory system. This plant contains a variety of flavonoids including oligomeric procyanidins (OPCs). Hawthorne is widely turned to in Europe for treating congestive heart failure (CHF). It may improve coronary artery blood flow, contractions of the heart muscle, exercise tolerance, and overall circulation.

L-Citrulline is an amino acid that the kidneys convert into L-arginine and nitric oxide. Therefore L-citrulline is included in formulations to boost nitric oxide production in the body. L-citrulline may help lower blood pressure in people whose blood pressure is trending high (pre-hypertension)* and it could also improve mild-to-moderate erectile dysfunction.

L-Arginine – is a semi-essential amino acid that enhances production of the vasodilator nitric oxide. Arginine is used clinically in conditions that are improved by vasodilation like heart failure, kidney failure, erectile dysfunction, and intermittent claudication. Trials show arginine can improve erectile dysfunction, sperm count and sperm quality.

Serving Size: 2 Capsules
Servings Per Container: 60
Amount Per Serving
Vitamin C (as Ascorbic Acid) 100 mg
Vitamin B12 (Methylcobalamin) 100 mcg
Folate 100 mcg
(as Quatrefolic® (equivalent to 200 mcg of
[6S]-5-Methyltetrahydrofolic acid, glucosamine salt))
Beet Root Powder 200 mg
Activin® Grape Seed Extract 120 mg
(vitis vinifera) 100:1
Hawthorne 100 mg
L-Citrulline 100 mg
L-Arginine 100 mg

Other Ingredients: Vegetable Cellulose (Capsule), Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate